منابع مشابه
p16 in HPV-associated cancers
Infections with high-risk human papillomaviruses (HPV) account for approximately 5% of all human cancers. Cervical cancer, in particular, is almost universally caused by “high-risk” HPV infections and these HPVs also cause a large fraction of other anogenital tract cancers as well as oral carcinomas. The viral E6 and E7 proteins are the universal oncogenic drivers of HPV-associated cancers, and...
متن کاملHPV-associated Oropharyngeal Cancers--Are They Preventable?
It is not known whether a human papillomavirus (HPV)-induced oropharyngeal precancerous lesion could be identified by screening with a pap test equivalent or whether one even exists. In this issue of the journal (beginning on page 1378), Fakhry and colleagues report their results showing that cytologic evaluation of the oropharynx, although useful in detecting invasive oropharyngeal cancers, ma...
متن کاملEditorial: HPV-Associated Cancers, Socio-Economic Disparity, and Vaccination
I am privileged to guest edit this Frontiers Research Topic addressing HPV infection and cancer disparities with the expert assistance of Dr. Silvia De Sanjose and Dr. Ala-Eddin Al Moustafa. We are, hereby, thankful to authors of manuscripts who had responded and enriched the topic with their valuable contributions. The findings of these manuscripts are interesting and contribute to our underst...
متن کاملImmunopathogenesis of HPV-Associated Cancers and Prospects for Immunotherapy
Human papillomavirus (HPV) infection is a causative factor for various cancers of the anogenital region and oropharynx, and is supposed to play an important cofactor role for skin carcinogenesis. Evasion from immunosurveillance favors viral persistence. However, there is evidence that the mere presence of oncogenic HPV is not sufficient for malignant progression and that additional tumor-promot...
متن کاملNew Approaches to Immunotherapy for HPV Associated Cancers
Cervical cancer is the second most common cancer of women worldwide and is the first cancer shown to be entirely induced by a virus, the human papillomavirus (HPV, major oncogenic genotypes HPV-16 and -18). Two recently developed prophylactic cervical cancer vaccines, using virus-like particles (VLP) technology, have the potential to prevent a large proportion of cervical cancer associated with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: memo - Magazine of European Medical Oncology
سال: 2019
ISSN: 1865-5041,1865-5076
DOI: 10.1007/s12254-019-00551-6